Skip to main content
. Author manuscript; available in PMC: 2021 Apr 26.
Published in final edited form as: Nat Metab. 2020 Oct 26;2(11):1248–1264. doi: 10.1038/s42255-020-00288-1

Extended Data Fig. 7. Cardiac function of cMPC1−/− after switching ketogenic diet to regular chow.

Extended Data Fig. 7

10-week-old control and cMPC1−/− mice were fed a Keto Diet for 8 weeks and then 50% of mice of each genotype were switched to regular chow for 6 weeks. The feeding scheme is shown in panel (a). LV mass (b) and ejection fraction (c) were determined via echocardiography at the age of 22 weeks (4 weeks after chow switch). Heart weight and tibia length (d) was determined at the age of 24 weeks. Sample sizes: n=10 (Control-2920X), n=8 (cMPC1−/−−2920X), n=9 (Control-Keto), n=8 (cMPC1−/−-Keto). Data are presented as mean ± SEM and P values were determined by two-way ANOVA followed by Tukey multiple comparison test.