Table 2.
The ROC curve analysis for pre-POI prediction.
| Variable | AUC | 95% CIb | cutoff | Sensitivity | Specificity | P value |
|---|---|---|---|---|---|---|
| AMH | 0.932 | 0.918-0.945 | 1.211 (ng/mL) | 79.74% | 99.80% | <0.001 |
| AFC | 0.868 | 0.848-0.885 | 5 | 69.53% | 85.91% | <0.001 |
| FSH/LH ratio | 0.749 | 0.726-0.772 | 2.11 | 62.44% | 81.05% | <0.001 |
| Inhibin B | 0.704 | 0.679-0.727 | 31.74 (pg/mL) | 46.59% | 89.06% | <0.001 |
| AMH+AFC | 0.948 | 0.935-0.959 | – | 84.08% | 95.68% | <0.001 |
| AMH + FSH/LH ratio | 0.932 | 0.918-0.945 | – | 79.95% | 99.90% | <0.001 |
| AMH + Inhibin B | 0.932 | 0.917-0.945 | – | 81.58% | 97.67% | <0.001 |
| AFC + FSH/LH ratio | 0.884 | 0.866-0.900 | – | 77.83% | 83.85% | <0.001 |
| AFC + Inhibin B | 0.880 | 0.862-0.897 | – | 77.40% | 82.41% | <0.001 |
| FSH/LH + Inhibin B | 0.715 | 0.691-0.739 | – | 49.88% | 86.83% | <0.001 |
| AMH + AFC + FSH/LH ratio | 0.948 | 0.935-0.959 | – | 84.04% | 95.58% | <0.001 |
| AMH + AFC + Inhibin B | 0.948 | 0.935-0.959 | – | 84.88% | 95.16% | <0.001 |
AMH, anti-müllerian hormone; AFC, antral follicle count; ROC, receiver-operator characteristic curve; AUC, the area under the curve.
bBinomial exact test.