Table 1. Comparison of baseline sample characteristics between responders and nonresponders and between remitters and nonremitters.
| Variables | Total (n = 94) | Response after six ketamine infusions | Remission after six ketamine infusions | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Responders (n = 64) | Nonresponders (n = 30) | Statistics | Remitters (n = 48) | Nonremitters (n = 46) | Statistics | ||||
| N (%) | N (%) | N (%) | X2 | p | N (%) | N (%) | X2 | p | |
| Female | 50 (53.2) | 35 (54.7) | 15 (50.0) | 0.2 | 0.67 | 22 (45.8) | 28 (60.9) | 2.1 | 0.14 |
| Employment | 38 (40.4) | 29 (45.3) | 9 (30.0) | 2.0 | 0.16 | 22 (45.8) | 16 (34.8) | 1.2 | 0.28 |
| Married | 50 (53.2) | 35 (54.7) | 15 (50.0) | 0.2 | 0.67 | 27 (56.3) | 23 (50.0) | 0.4 | 0.54 |
| Mean (SD) | Mean (SD) | Mean (SD) | T/Z | p | Mean (SD) | Mean (SD) | T/Z | p | |
| Age (years) | 34.6 (11.6) | 35.1 (11.2) | 33.4 (12.5) | −0.7 | 0.50 | 34.8 (10.9) | 34.3 (12.4) | −0.2 | 0.83 |
| Education (years) | 12.4 (3.3) | 12.8 (3.2) | 11.4 (3.4) | −2.0 | 0.049 | 12.6 (3.2) | 12.1 (3.4) | −0.6 | 0.53 |
| BMI (kg/m2) | 22.4 (3.6) | 22.5 (3.5) | 22.2 (3.8) | −0.4 | 0.66 | 22.7 (3.9) | 22.1 (3.2) | 0.8 | 0.43 |
| Duration of illness (months) | 102.5 (98.3) | 106.3 (101.7) | 94.5 (91.9) | —a | 0.51 | 107.3 (101.4) | 97.6 (95.9) | —a | 0.58 |
| Baseline MADRS scores | 31.9 (7.6) | 31.8 (7.6) | 32.2 (7.6) | 0.3 | 0.80 | 30.6 (7.3) | 33.3 (7.7) | −1.8 | 0.08 |
| pBDNF concentrations (ng/ml) | 10.1 (6.2) | 11.0 (6.2) | 8.0 (5.5) | —a | 0.01 | 10.1 (5.8) | 9.2 (6.4) | —a | 0.045 |
Notes.
a
Mann–Whitney U test.
Bolded values are p<0.05.
- pBDNF
- plasma brain derived neurotrophic factor
- BMI
- Body Mass Index
- MADRS
- Montgomery-Asberg Depression Rating Scale
- SD
- standard deviation