Skip to main content
. 2021 Mar 29;9:e10989. doi: 10.7717/peerj.10989

Table 2. Comparison of MADRS scores and pBDNF concentrations between responders and nonresponders and between remitters and nonremitters in patients with unipolar and bipolar depression using linear mixed model analysis.

Outcomes Variables Group-by-time interaction Time main effect Group main effect
F p F p F p
Responders vs. nonresponders MADRS scores 59.79 <0.001 223.39 <0.001 59.32 <0.001
pBDNF concentrations (ng/ml) 0.04 0.837 8.55 <0.001 3.90 0.024
Remitters vs. nonremitters MADRS scores 74.95 <0.001 263.13 <0.001 29.52 <0.001
pBDNF concentrations (ng/ml) 0.02 0.888 6.40 0.003 2.61 0.079

Notes.

Bolded values are p < 0.05.

pBDNF
plasma brain derived neurotrophic factor
MADRS
Montgomery-Asberg Depression Rating Scale