TABLE 1.
Demographic data for ATN groups
| A+T+N+ | A+T+N‐ | A+T‐N‐ | A+T‐N+ | A‐T+N+ | A‐T+N‐ | A‐T‐N+ | A‐T‐N‐ | |
|---|---|---|---|---|---|---|---|---|
| N (%) | 97 (23) | 4 (1) | 34 (8) | 3 (1) | 87 (20) | 34 (8) | 24 (6) | 137 (33) |
| Baseline cognitive status: | ||||||||
| MCI N (%) | 72 (74) | 4 (100) | 18 (53) | 2 (67) | 49 (56) | 13 (38) | 10 (42) | 58 (42) |
| SCI N (%) | 25 (26) | 0 | 16 (47) | 1 (33) | 38 (44) | 21 (62) | 14 (58) | 79 (58) |
| Sex (% female) | 57 | 25 | 53 | 33 | 59 | 53 | 67 | 57 |
| Age (years) | 68.1 ± 6.9** | 68.3 ± 6.0 | 63.6 ± 8.4 | 70.3 ± 7.2* | 65.7 ± 7.3** | 61.3 ± 5.9 | 66.4 ± 8.6* | 61.1 ± 7.5 |
| Education (years) | 12.0 ± 3.3 | 12.0 ± 3.3 | 12.2 ± 3.9 | 11.0 ± 4.2 | 12.1 ± 3.6 | 12.8 ± 3.3 | 13.1 ± 2.9 | 13.2 ± 3.4 |
| MMSE | 28.0 ± 1.5 | 27.0 ± 1.0 | 28.5 ± 1.7 | 28.3 ± 0.6 | 28.6 ± 1.3 | 29.1 ± 1.3 | 28.3 ± 1.6 | 28.8 ± 1.2 |
| APOE ε4% (1 allele/2 alleles) | 49 / 26** | 25 / 50** | 36 / 21** | 100 / 0* | 45 / 5* | 12 / 9 | 38 / 0 | 29 / 3 |
Data are presented as the mean ± SD. The A‐T‐N‐ group was compared to other ATN groups. APOE ε4% (1 allele/2 alleles): percentage of study participant with one or two APOE ε4 alleles.
*
P‐value <.05 versus A‐T‐N‐.
**
P‐value <.001 versus A‐T‐N‐.