Table 4.

Subgroups analysis of odds ratios of the triglyceride–glucose index with diabetic nephropathy in patients with type 2 diabetes

Subgroups	Model 1		Model 2		Model 3
	OR (95% CI)	P‐value	OR (95% CI)	P‐value	OR (95% CI)	P‐value
Age
≥60 years	1.74 (1.05–2.89)	0.031	2.30 (1.21–4.37)	0.011	2.24 (1.07–4.68)	0.032
<60 years	2.32 (1.53–3.53)	0.000	2.25 (1.40–3.61)	0.001	2.14 (1.27–3.62)	0.004
HbA1C
≥7.0%	2.47 (162–3.77)	0.000	2.50 (1.55–4.02)	0.000	2.28 (1.37–3.80)	0.002
<7.0%	1.40 (0.75–2.60)	0.295	1.39 (0.67–2.88)	0.373	1.52 (0.72–3.23)	0.275
eGFR
<90 mL/min/1.73 m2	0.85 (0.50–1.47)	0.565	1.01 (0.50–2.01)	0.983	1.34 (0.57–3.15)	0.509
≥90 mL/min/1.73 m2	2.99 (1.89–4.73)	0.000	3.00 (1.81–4.97)	0.000	2.60 (1.49–4.54)	0.001
Hypertension
Yes	1.53 (0.98–2.39)	0.063	1.64 (0.98–2.72)	0.058	2.04 (1.13–3.67)	0.018
No	2.23 (1.41–3.52)	0.001	2.42 (1.43–4.09)	0.001	1.89 (1.05–3.40)	0.034

Model 1: adjusted for age and sex; model 2: model 1 + bodyweight, disease duration, presence of hypertension and serum uric acid; model 3: model 2 + glycated hemoglobin (HbA_1C).

CI, confidence interval; eGFR, estimated glomerular filtration rate; OR, odds ratio.