Table. 1.
Patient characteristics.
| Patients with low lipid burden lesions (n = 40) | Patients with high lipid burden lesions (n = 9) | P | |
|---|---|---|---|
| Age [years] | 66.17 ± 11.32 | 65.5 ± 10.72 | 0.920 |
| Male gender | 32 (80%) | 5 (55%) | 0.113 |
| Body mass index [kg/m2] | 26.7 (IQR 25.23, 27.93) | 25.15 (IQR 20.70, 36.09) | 0.771 |
| NSTEMI/UA/SCAD | 4 (10%)/20 (50%)/16 (30%) | 0/5 (55%)/4 (45%) | 0.433 |
| Risk factors | |||
| Hypertension | 36 (90%) | 8 (88%) | 0.634 |
| Hyperlipidemia | 40 (100%) | 9 (100%) | – |
| Diabetes mellitus | 11 (27%) | 6 (67%) | 0.058 |
| Current smoking | 3 (7%) | 1 (11%) | 0.714 |
| Pharmacological therapy | |||
| Acetylsalicylic acid | 38 (95%) | 8 (88%) | 0.765 |
| Thienopyridine | 27 (67%) | 3 (33%) | 0.153 |
| Beta-adrenergic antagonist | 32 (80%) | 6 (67%) | 0.519 |
| Calcium channel antagonist | 10 (25%) | 5 (56%) | 0.148 |
| ARB/ACEI | 27 (67%) | 6 (67%) | 0.732 |
| Statin | 36 (90%) | 9 (100%) | 0.623 |
| Other lipid-lowering therapy | 4 (10%) | 2 (22%) | 0.654 |
| Oral antidiabetics | 10 (25%) | 5 (56%) | 0.148 |
| Insulin | 1 (2%) | 1 (11%) | 0.792 |
| Laboratory results | |||
| Total cholesterol [mg/dL] | 139 (IQR 127, 153) | 171 (IQR 146.92, 244.64) | 0.031 |
| LDL cholesterol [mg/dL] | 76 (IQR 69, 93) | 99.00 (IQR 69.69, 132.03) | 0.120 |
| HDL cholesterol [mg/dL] | 40.00 (IQR 36.76, 46.00) | 44.50 (IQR 38.67, 50.16) | 0.401 |
| Triglyceride [mg/dL] | 102.02 (IQR 91.58, 115.19) | 154.50 (IQR 98.10, 355.03) | 0.012 |
| GRF [mL/min/1.73 m2] | 72.40 ± 15.93 | 67.62 ± 25.84 | 0.473 |
NSTEMI — non-ST-segment elevation myocardial infarction, UA — unstable angina, SCAD — stable coronary artery disease, ARB — angiotensin II receptor blocker, ACEI — angiotensin-converting-enzyme inhibitor; LDL — low density lipoprotein, HDL — high-density lipoprotein, GRF — glomerular filtration rate; IQR — interquartile range