Table 2.

Near-infrared spectroscopy and intravascular ultrasound results of the stented segment.

Parameters	Low lipid burden lesions (n = 41)			High lipid burden lesions (n = 9)
	Pre-stenting	Post-stenting	P	Pre-stenting	Post-stenting	P
Stented segment
ROI [mm]	21.98 ± 9.01	21.96 ± 8.98	0.804	25.71 ± 15.38	25.70 ± 15.39	0.346
MLD [mm]	1.64 ± 0.31	2.23 ± 0.37	< 0.001	1.53 ± 0.13	2.28 ± 0.34	< 0.001
MLA [mm2]	2.65 ± 1.21	5.31 ± 1.68	< 0.001	2.94 ± 1.40	6.15 ± 1.39	< 0.001
Stenosis (MLA) on reference [%]	55.36 ± 13.01	17.90 ± 14.38	< 0.001	57.63 ± 10.19	19.00 ± 14.78	0.006
Lumen volume [mm3]	98.80 (63.15, 131.45)	128.30 (86.97, 185.37)	< 0.001	96.70 (69.10, 112.62)	181.30 (76.22, 266.37)	0.004
EEM volume [mm3]	226.70 (140.77, 315.82)	288.60 (169.42, 377.62)	< 0.001	244.40 (149.55, 379.10)	317.30 (144.47, 535.52)	0.012
ΔEEM volume [mm3]	46.45 (21.50, 74.85)			67.40 (16.22, 116.62)		0.423
Plaque volume [mm3]	124.50 (68.00, 186.20)	101.10 (67.87, 165.95)	< 0.001	144.70 (80.47, 274. 25)	97.60 (56.82, 223.45)	0.004
ΔMPV [mm3]	13.50 (1.50, 28.84)			28.00 (22.60, 57.10)		0.019
maxLCBI4 [mm]	339.07 ± 268.22	124.60 ± 160.96	< 0.001	564.11 ± 166.82	258.11 ± 234.24	0.004
EEM area [mm2]	10.00 (7.50, 11.60)	11.30 (9.27, 13.25)	< 0.001	12.70 (12.10, 13.47)	13.10 (11.72, 16.20)	0.820
EEM eccentricity	0.09 (0.07, 0.15)	0.09 (0.06, 0.13)	0.551	0.09 ± 0.01	0.11 ± 0.04	0.341
Lumen eccentricity	0.09 (0.06, 0.14)	0.13 (0.08, 0.18)	0.038	0.17 ± 1.12	0.20 ± 0.10	0.181
Total plaque area [mm2]	7.4 (5.12, 8.62)	4.7 (3.67, 6.40)	< 0.001	11.51 ± 5.01	5.72 ± 1.80	0.009
Plaque burden [%]	72.19 ± 8.12	55.03 ± 6.87	< 0.001	79.26 ± 8.57	53.0 ± 9.9	< 0.001
Remodeling index	0.87 ± 0.23	1.09 ± 0.27	< 0.001	1.23 ± 0.11	1.20 ± 0.25	0.739

ROI — region of interest; MLD — minimal lumen diameter; MLA — minimal lumen area; EEM — external elastic lamina; maxLCBI4 mm — maximal lipid core burden index in four millimeters; ΔMPV — delta plaque volume