Table 2.
Peptide sequences
| RFRP group (LPXRFamide) | ||
|---|---|---|
| Agonist [relative position in final peptide (Mouse)] | Absolute position in propeptide | Sequence |
| RFRP-3 (3–10) [SHFPSLPQRF-NH2] | Pro-RFRPs (116–125) | Phe-Pro-Ser-Leu-Pro-Gln-Arg-Phe-NH2 |
| RFRP-1 (4–15) [ANKVPHSAANLPLRF-NH2] | Pro-RFRPs (83–94) | Val-Pro-His-Ser-Ala-Ala-Asn-Leu-Pro-Leu-Arg-Phe-NH2 |
| NPFF group (XPQRFamide) | ||
| Agonist (relative position in final peptide [mouse]) | Absolute position in propeptide | Sequence |
| NPFF [FLFQPQRF-NH2] | Pro-NPFF (75–82) | Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe-NH2 |
| NPAF-like (4–11) [QFWSLAAPQRF-NH2] | Pro-NPFF (101–111) | Ser-Leu-Ala-Ala-Pro-Gln-Arg-Phe-NH2 |
| Other | ||
| Prolactin-releasing peptide-20 (PrRP-20) | Thr-Pro-Asp-Ile-Asn-Pro-Ala-Trp-Tyr-Thr-Gly-Arg-Gly-Ile-Arg-Pro-Val-Gly-Arg-Phe-NH2 | |
| dNPA (Synthetic NPFF2R agonist) | D.Asn-Pro-(N-Me)Ala-Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe-NH2 |
Bold represents either LPXRF or XPQRF sequence, whereas italics represents the X.