Table 1.
Overall (n=45) |
|
Age (years) | |
Median (minimum, maximum) | 67.6 (39.9, 84.6) |
Gender | |
female | 19 (42%) |
male | 26 (58%) |
Histology | |
Adeno | 34 (76%) |
Squamous | 10 (22%) |
Sarcomatoid | 1 (2%) |
PD-L1 expression | |
0 | 5 (11%) |
>0–<10 | 0 (0%) |
≥10 | 28 (62%) |
Not reported | 12 (27%) |
T status | |
1 | 10 (22%) |
2 | 8 (18%) |
3 | 8 (18%) |
4 | 19 (42%) |
N status | |
0 | 7 (16%) |
1 | 3 (7%) |
2 | 15 (33%) |
3 | 20 (44%) |
M status | |
0 | 9 (20%) |
1 | 36 (80%) |
UICC stage | |
3 | 9 (20%) |
4 | 36 (80%) |
Immunotherapy regimen | |
Atezolizumab | 3 (7%) |
Nivolumab | 21 (47%) |
Pembrolizumab | 20 (44%) |
Ipilimumab/nivolumab | 1 (2%) |
Treatment line | |
First line | 25 (56%) |
Non-first line | 20 (44%) |
Prior surgery | 11 (24%) |
Prior radiotherapy | 17 (38%) |
Prior chemotherapy | 28 (62%) |
Months immunotherapy until PET | |
Median (minimum, maximum) | 30.7 (24.2, 53.0) |
Months until best objective response | |
Median (minimum, maximum) | 10.4 (1.1, 30.1) |
Response according to RECIST | |
PR | 36 (80%) |
SD | 9 (20%) |
PET, positron emission tomography.