Table 1.
Comparison of outcomes after euploid frozen embryo transfer stratified by inner cell mass and trophectoderm blastocyst grades.
| Grade | euFET (n) | Implantationa | P valueb | Clinical pregnancyc | P valueb | Live birthd | P valueb | Clinical miscarriagee | P valueb | Biochemical pregnancy lossf | P valueb |
|---|---|---|---|---|---|---|---|---|---|---|---|
| ICM | |||||||||||
| A | 217 | 185 (85) | .24 | 164 (76) | .26 | 145 (67) | .08 | 18 (11) | .38 | 19 (10) | .45 |
| B | 405 | 327 (81) | 293 (72) | 244 (60) | 47 (16) | 31 (9) | |||||
| C | 38 | 29 (81) | 24 (63) | 19 (50) | 5 (21) | 5 (17) | |||||
| TE | |||||||||||
| A | 312 | 259 (83) | .38 | 232 (74) | .09 | 203 (65) | .01 | 28 (12) | .25 | 24 (9) | .37 |
| B | 277 | 228 (82) | 205 (75) | 172 (62) | 31 (15) | 22 (10) | |||||
| C | 71 | 54 (76) | 44 (62) | 33 (46) | 11 (25) | 9 (17) |
Note: Values are number (percentage) unless specified otherwise. euFET = euploid frozen embryo transfer; ICM = inner cell mass; TE = trophectoderm.
Implantation was defined as β-human chorionic gonadotropin level > 5 mIU/mL.
Chi-square analysis.
Clinical pregnancy was defined as a visualized gestational sac.
Live birth was defined as delivery of a neonate at or beyond 24 weeks.
Clinical miscarriage rate was calculated per clinical pregnancy.
Biochemical pregnancy loss was defined as loss of pregnancy after conception and before visualization of a gestational sac on transvaginal ultrasound. Biochemical pregnancy loss rate was calculated per implantation.