Table 3. Changes in clinical measures and chemistries (mean (SD)) from baseline to week 8 with baseline values imputed for missing.
| Complete Case | ||||||||||
| All Participants | Baseline High Risk Only | |||||||||
| n | Baseline | 8 weeks | Change | P value | n | Baseline | 8 weeks | Change | P value | |
| Weight (lb) | 399 | 169.5 (41.8) | 168.0 (41.9) | -1.51 (4.4) | < .001 | 194 | 193.2 (44.7) | 191.7 (44.9) | -1.5 (5.0) | <0.001 |
| BMI (kg/m2) | 392 | 31.6 (8.2) | 31.4 (8.2) | -0.3 (0.8) | < .001 | 187 | 37.8 (7.8) | 37.5 (7.9) | -0.3 (1.0) | <0.001 |
| Waist Circumference (inches) | 388 | 38.1 (5.2) | 37.4 (5.4) | -0.7 (2.0) | < .01 | 210 | 40.6 (4.5) | 39.9 (5.1) | -0.8 (2.4) | <0.001 |
| Hemoglobin A1C (%) | 133 | 5.91 (1.2) | 5.76 (0.86) | -0.15 (0.7) | < .05 | 56 | 6.8 (1.5) | 6.4 (1.0) | -0.39 (1.0) | <0.01 |
| Glucose (mg/dl) | 392 | 115.9 (46.1) | 112.8 (39.4) | -3.1 (40.0) | 0.13 | 205 | 140.3 (52.3) | 126.2 (47.4) | -14.1 (48.9) | <0.001 |
| Systolic Blood Pressure (mm Hg) | 397 | 125.6 (14.6) | 122.9 (13.6) | -2.7 (12.6) | < .01 | 108 | 144.6 (10.1) | 134.9 (12.6) | -9.9 (14.8) | <0.001 |
| Diastolic Blood Pressure (mm Hg) | 396 | 78.9 (10.1) | 78.1 (9.8) | -0.7 (11.3) | 0.20 | 112 | 90.1 (7.8) | 82.5 (8.4) | -7.7 (10.6) | <0.001 |
| Cholesterol (mg/dl) | 371 | 188.8 (38.3) | 183.0 (36.1) | -5.8 (27.8) | < .01 | 125 | 231.2 (23.3) | 210.4 (35.2) | -20.7 (30.6) | <0.001 |
| Knowledge | 303 | 75.6 (18.6) | 85.9 (13.9) | 10.6 (17.1) | < .001 | 61 | 45.3 (11.7) | 77.1 (12.4) | 31.8 (18.6) | <0.001 |
| Imputing Baseline for Missing Follow-Up Values | ||||||||||
| All Participants | Baseline High Risk Only | |||||||||
| n | Baseline | 8 weeks | Change | P value | n | Baseline | 8 weeks | Change | P value | |
| Weight (lb) | 622 | 169.0 (39.3) | 168.0 (39.4) | -1.0 (3.6) | < .001 | 285 | 191.3 (40.4) | 190.5 (40.6) | - 0.8 (3.9) | <0.001 |
| BMI (kg/m2) | 608 | 31.3 (7.7) | 31.1 (7.6) | -0.2 (0.7) | < .001 | 283 | 37.3 (7.0) | 37.1 (7.0) | -0.2 (0.8) | <0.001 |
| Waist Circumference (inches) | 606 | 38.0 (5.2) | 37.5 (5.4) | -0.4 (1.6) | < .001 | 316 | 40.6 (4.6) | 40.1 (5.0) | -0.5 (2.0) | <0.001 |
| Hemoglobin A1C (g/dl) | 200 | 6.1 (1.5) | 6.0 (1.3) | -0.2 (0.6) | 0.179 | 87 | 7.1 (1.8) | 6.8 (1.7) | -0.3 (0.9) | <0.01 |
| Glucose (mg/dl) | 616 | 120.9 (54.9) | 118.9 (51.7) | -2.0 (32.0) | 0.131 | 350 | 145.0 (62.5) | 136.7 (61.2) | -8.3 (38.0) | <0.001 |
| Systolic Blood Pressure (mm Hg) | 618 | 125.5 (14.5) | 123.8 (13.9) | -1.7 (10.2) | < .001 | 179 | 143.9 (9.7) | 137.9 (11.8) | -6.0 (12.5) | <0.001 |
| Diastolic Blood Pressure (mm Hg) | 619 | 79.1 (10.7) | 78.6 (10.5) | -0.5 (9.0) | 0.196 | 170 | 90.7 (10.7) | 85.7 (11.8) | -5.1 (9.3) | <0.001 |
| Cholesterol (mg/dl) | 606 | 189.7 (38.8) | 186.1 (37.7) | -3.5 (21.9) | < .001 | 215 | 231.0 (25.7) | 218.9 (34.2) | -12.1 (25.4) | <0.001 |
| Knowledge | 470 | 75.6 (18.6) | 82.4 (16.7) | 6.8 (14.6) | < .001 | 103 | 45.8 (11.6) | 64.7 (22.3) | 18.8 | < .001 |
Notes
1Knowledge is presented as percentage correct of 20 items.