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. 2021 Apr 1;16(4):e0249276. doi: 10.1371/journal.pone.0249276

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© 2021 Deng et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 2 — A, Paw swelling induced by CFA in mice. B, Paw withdrawal latency of mice was detected by hot plate test on the 1^st, 3^rd, 5^th, and 7^th day. Data represent mean ± SD (n = 6). **p < 0.01 compared with the control group; ^#p < 0.05, ^##p < 0.01, ^###p < 0.001 compared with the model group.