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. 2021 Apr 1;16(4):e0249276. doi: 10.1371/journal.pone.0249276

Table 1. Analgesic activity of aconitine in hot plate test in mice.

Group Reaction time / s Pain threshold improvement rate
30 min 30 min
Control 3.0±1.35 ---
Aspirin (200 mg/kg) 5.0±1.42 19.21%**
Low dosage AC (0.3 mg/kg) 4.2±0.65 17.12%**
High dosage AC (0.9 mg/kg) 7.6±1.42*** 20.27%**

Data represent mean ± SD (n = 6).

**p < 0.01, and

***p < 0.001 compared with the control group.