. 2021 Apr 1;16(4):e0249276. doi: 10.1371/journal.pone.0249276

Table 3. Analgesic activities of aconitine on different pain models of mice.

Group	Acetic acid writhing test (inhibition rate, %)	Hot plate test (Pain threshold improvement rate, %)	Formalin induced nociception assay (120 min, inhibition rate of licking time, %)		CFA induced nociception assay (pain threshold improvement rate, %)
Group	Acetic acid writhing test (inhibition rate, %)	Hot plate test (Pain threshold improvement rate, %)	First phase	Second phase	7^th compare with 1^st
Aspirin group (200 mg/kg)	75	19.21	50.31	25.97	152.03
Low dosage AC (0.3 mg/kg)	68	17.12	33.23	20.25	131.33
High dosage AC (0.9 mg/kg)	76	20.27	58.92	68.32	35.11