Table 3. Analysis of prognostic factors related to mortality in patients with chronic pulmonary aspergillosis.
| Univariate | Final multivariate | |||
|---|---|---|---|---|
| Hazard ratio (95% CI) | p-value | Hazard ratio (95% CI) | p-value | |
| Age | 1.05 (1.03–1.07) | <0.001 | 1.05 (1.02–1.08) | <0.001 |
| Male sex | 2.31 (1.37–3.89) | 0.002 | 2.48 (1.34–4.59) | 0.004 |
| Body mass index < 18.5 kg/m2 | 1.88 (1.25–2.83) | 0.002 | 1.87 (1.20–2.90) | 0.005 |
| Underlying pulmonary conditions | ||||
| Previous pulmonary tuberculosis | 0.91 (0.61–1.34) | 0.62 | 1.22 (0.76–1.95) | 0.42 |
| Non-tuberculous mycobacterium | 1.05 (0.70–1.58) | 0.81 | 0.85 (0.52–1.38) | 0.51 |
| Emphysema | 1.00 (0.67–1.47) | 0.98 | 0.69 (0.44–1.06) | 0.092 |
| Pneumothorax | 1.63 (0.66–4.00) | 0.29 | 0.96 (0.34–2.70) | 0.94 |
| Bronchiectasis | 0.71 (0.41–1.23) | 0.22 | 1.43 (0.74–2.75) | 0.28 |
| Thoracic surgery | 1.22 (0.68–2.18) | 0.51 | 1.04 (0.55–1.95) | 0.91 |
| Interstitial lung abnormalities | 2.36 (1.55–3.58) | <0.001 | 1.76 (1.06–2.92) | 0.029 |
| Presence of aspergilloma | 1.55 (1.07–2.25) | 0.021 | 1.59 (1.04–2.45) | 0.033 |
| Smoking history | 1.62 (0.99–2.65) | 0.054 | - | |
| Auto Immune Diseases | 1.71 (0.79–3.71) | 0.17 | - | |
| Use of systemic corticosteroids | 2.84 (1.50–5.38) | 0.001 | 1.93 (0.91–4.09) | 0.085 |
| Albumin | 0.40 (0.30–0.53) | <0.001 | 0.56 (0.38–0.83) | 0.004 |
| C-reactive protein | 1.06 (1.04–1.09) | <0.001 | 1.02 (0.99–1.06) | 0.23 |