Table 2. Selected target genes of the most expressed miRNAs in Echinococcus multilocularis.
| miRNA | Gene ID | Gene Description a | KEGG pathway | Conservation |
|---|---|---|---|---|
| emu-miR-10-5p | EmuJ_000389600 | Mitogen activated protein kinase kinase kinase | MAPK signaling pathway | E. granulosus and T. solium |
| EmuJ_000188500 | Protein pangolin J | Wnt signaling pathway | E. granulosus and T. solium | |
| EmuJ_001095100 | Homeobox protein Meis1 | -- | E. granulosus and T. solium | |
| emu-miR-1-3p | EmuJ_000485800 | Ezrin-like protein (Elp) | Regulation of actin cytoskeleton | T. solium |
| EmuJ_001049900 | Dynein light chain | Cytoskeleton proteins | E. granulosus | |
| EmuJ_000596700 | Dynein heavy chain | Cytoskeleton proteins | E. granulosus | |
| EmuJ_000178100 | Activin; Tgf beta family | TGF-beta signaling pathway | E. granulosus | |
| emu-miR-9-5p | EmuJ_000108300 | Carbonic anhydrase | -- | E. granulosus |
| EmuJ_000955500 | Peregrin | Chromosome and associated proteins | E. granulosus | |
| emu-miR-4989-3p | EmuJ_000495100 | General transcription factor IIH subunit |
Basal transcription factors |
E. granulosus |
| EmuJ_001177300 | Basic leucine zipper bZIP transcription factor | -- | E. granulosus | |
| emu-let-7-5p | EmuJ_000379600 | Nuclear receptor 2DBD gamma | -- | E. granulosus and T. solium |
| EmuJ_000813900 | Homeobox protein Hox B4a | -- | E. granulosus and T. solium | |
| EmuJ_001053100 | Transcription factor sum | -- | E. granulosus and T. solium | |
|
emu-miR-71-5p |
EmuJ_001059700 | Aurora kinase A | Oocyte meiosis | T. solium |
| EmuJ_000646000 | Mitotic checkpoint serine:threonine protein | Cell cycle | E. granulosus | |
| EmuJ_000456500 | G1:S specific cyclin D1 | Cell cycle | E. granulosus and T. solium | |
| EmuJ_000974400 | Cyclin G2 | p53 signaling pathway | E. granulosus | |
| EmuJ_000866400 | Polycomb group RING finger protein 2 | Signaling pathways regulating pluripotency of stem cells | E. granulosus and T. solium | |
| EmuJ_001141100 | Regulatory associated protein of mTOR | mTOR signaling pathway | E. granulosus | |
| EmuJ_000468300 | Target of rapamycin complex 2 subunit MAPKAP1 | mTOR signaling pathway | E. granulosus and T. solium | |
| EmuJ_000445850 | Mitochondrial import inner membrane translocase subunit Tim23 putative | Longevity regulating pathway - worm | T. solium |
a Gene Description according to WBPS14 (WS271).