Table 4.
Diagnostic accuracy of TG/HDL-C and TyG in predicting lifetime cardiovascular risk and their optimal cutoff values.
| Predictors | Overall | Men | Women |
|---|---|---|---|
| Value (CI 95%) | Value (CI 95%) | Value (CI 95%) | |
| TG/HDL-C | |||
| Optimal cutoffa | 2.64 | 3.90 | 2.64 |
| AUC | 0.77 (0.71–0.83) | 0.80 (0.70–0.90) | 0.74 (0.65–0.83) |
| Sensitivity | 0.86 (0.76–0.94) | 0.66 (0.49–0.80) | 0.86 (0.68–0.96) |
| Specificity | 0.60 (0.54–0.67) | 0.87 (0.74–0.95) | 0.60 (0.52–0.67) |
| PPV | 0.39 (0.33–0.60) | 0.81 (0.64–0.90) | 0.26 (0.20–0.58) |
| NPV | 0.94 (0.88–0.95) | 0.75 (0.60–0.90) | 0.96 (0.90–0.97) |
|
| |||
| TyG | |||
| Optimal cutoffa | 9.04 | 8.95 | 9.04 |
| AUC | 0.80 (0.74–0.86) | 0.79 (0.69–0.89) | 0.80 (0.72–0.88) |
| Sensitivity | 0.64 (0.51–0.76) | 0.68 (0.51–0.82) | 0.66 (0.46–0.82) |
| Specificity | 0.83 (0.77–0.88) | 0.80 (0.66–0.91) | 0.82 (0.76–0.88) |
| PPV | 0.53 (0.44–0.66) | 0.74 (0.58–0.86) | 0.38 (0.29–0.60) |
| NPV | 0.88 (0.82–0.92) | 0.76 (0.60–0.88) | 0.94 (0.87–0.96) |
AUC, area under the curve; TG/HDL-C, triglycerides to HDL-cholesterol ratio; TyG, triglyceride glucose index; PPV, positive predictive value; NPV, negative predictive value.