Figure 1.

Overview of the establishment of PNVP model. A) Schematic diagram demonstrates early cellular and molecular processes that occur during the initial vascularization of the developing brain from the perineural vascular plexus in humans. B) (i) Overview of a custom designed microfluidics plate containing 20 devices per 96-well plate. (ii) Overview of one device describing different chambers and side channels. (iii) Schematic diagram demonstrates the cross-sectional view of the establishment of PNVP model in vitro.