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. 2021 Feb 16;54(4):e13005. doi: 10.1111/cpr.13005

FIGURE 3.

FIGURE 3

Gene expression patterns and signalling pathways associated with FXR knockout in renal I/R injury. RNA‐seq analysis was used to reveal the DEGs between wild‐type and Fxr−/− mice (n = 4 per group). (A) Cluster analysis of DEGs between two groups. Red means upregulated and green means downregulated. (B) The five most enriched KEGG pathways between wild‐type and Fxr−/− mice. (C) Cluster analysis of DEGs involved in the most enriched KEGG pathways