Table 3.
Comparison of patients with or without pharmacological treatment response at 8-week and 6-month period stratified by sociodemographic characteristics and clinical variables
| Treatment response |
||||||
|---|---|---|---|---|---|---|
| 8 weeks |
χ2 or t (p) | 6 months |
χ2 or t (p) | |||
| Yes (N=29) | No (N=122) | Yes (N=57) | No (N=95) | |||
| Demographics | ||||||
| Age (years) | 40.07±14.44 | 37.54±10.84 | -0.885 (0.382) | 39.42±12.58 | 37.01±11.03 | -1.237 (0.218) |
| Gender | 1.299 (0.302) | 0.087 (0.867) | ||||
| Male | 16 (23.2) | 53 (76.8) | 25 (36.2) | 44 (63.8) | ||
| Female | 13 (15.9) | 69 (84.1) | 32 (38.6) | 51 (61.4) | ||
| Level of education | 0.030 (1.000) | 4.723 (0.034*) | ||||
| High school or less | 10 (20.0) | 40 (80.0) | 13 (25.5) | 38 (74.5) | ||
| College or higher | 19 (18.8) | 82 (81.2) | 44 (43.6) | 57 (56.4) | ||
| Marital status | 0.003 (1.000) | 0.255 (0.736) | ||||
| Married | 16 (19.0) | 68 (81.0) | 33 (39.3) | 51 (60.7) | ||
| Single | 13 (19.4) | 54 (80.6) | 24 (35.3) | 44 (64.7) | ||
| Clinical variables | ||||||
| Duration of illness (months) | 49.90±88.79 | 43.43±69.25 | -0.427 (0.670) | 48.91±89.29 | 42.04±61.35 | -0.561 (0.575) |
| Agoraphobia | 0.879 (0.448) | 0.169 (0.838) | ||||
| Yes | 21 (17.6) | 98 (82.4) | 46 (38.3) | 74 (61.7) | ||
| No | 8 (25.0) | 24 (75.0) | 11 (34.4) | 21 (65.6) | ||
| ETI (total sum) | ||||||
| All subtypes | 4.16±3.98 | 5.06±4.01 | 1.020 (0.310) | 3.96±3.90 | 5.41±3.98 | 2.126 (0.035*) |
| General subtype | 1.50±1.79 | 1.34±1.46 | -0.489 (0.626) | 1.26±1.57 | 1.41±1.50 | 0.598 (0.551) |
| Physical subtype | 1.59±1.47 | 1.95±1.68 | 1.023 (0.308) | 1.44±1.57 | 2.15±1.63 | 1.607 (0.010*) |
| Emotional subtype | 1.25±1.71 | 1.31±1.69 | 0.173 (0.863) | 1.07±1.61 | 1.42±1.72 | 1.235 (0.219) |
| Sexual subtype | 0.14±0.08 | 0.41±0.94 | 2.261 (0.026*) | 0.28±0.73 | 0.39±0.94 | 0.776 (0.439) |
| ASI (total sum) | 47.36±25.51 | 46.13±26.35 | -0.212 (0.832) | 44.75±25.54 | 47.50±26.46 | 0.602 (0.548) |
| PDSS (total sum) | 14.28±6.49 | 12.12±5.83 | -1.753 (0.082) | 13.82±5.72 | 11.73±6.03 | -2.105 (0.037*) |
| BDI-II (total sum) | 17.00±9.13 | 15.26±9.85 | -0.841 (0.402) | 14.33±9.05 | 16.46±10.10 | 1.291 (0.199) |
Values represent count (percent), mean±SD, and median (interquartile range).
*
p<0.05.
Criteria for treatment response: when the PDSS score at each time point is reduced by 40% or more compared to the PDSS score at the beginning of treatment, it is set as a treatment response. SD: standard deviation, ETI: Early Traumatic Inventory, ASI: Anxiety Sensitivity Inventory, PDSS: Panic Disorder Severity Scale, BDI: Beck Depression Inventory