Table 1.

Cohort 1 (no treatment): Patient characteristics and course of visual acuity

No.	Age	Sex	Mutation	Homo-/heteroplasmy	Initial visual acuity		Deterioration (time since onset)	Final visual acuity		Observation period (m)
					OD	OS		OD	OS
1	30	M	11778	Homoplasmy	0.10	0.05		0.05	0.05	87.00
2	26	M	3460	N/A	0.03	0.50		0.03	0.50	60.00
3	48	F	3460	Heteroplasmy	0.10	0.16		0.01	0.01	23.00
4	17	M	11778	Homoplasmy	1.00	0.05	0.3 (OD, 3 m)	0.04	0.04	72.00
5	12	M	11778	N/A	0.30	0.50		0.03	0.03	24.00

m months