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. 2021 Apr 1;12:2016. doi: 10.1038/s41467-021-22362-2

Fig. 3. Crystal structures of inhibitors in complex with the SARS-CoV-2 3CL protease.

Fig. 3

Structure of compound 4 (a), GC376 (b), or MAC-5576 (c) bound to SARS-CoV-2 3CLpro. Protomer A is denoted in green and protomer B is denoted in cyan. The Fo–Fc omit map, contoured at 3σ (gray), for compound 4 (d), GC376 (e), and MAC-5576 (f).