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. 2021 Apr 1;11:7353. doi: 10.1038/s41598-021-86802-1

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Miami plot showing the association of SNP rs12658032 with ADHD compared to MDD. Miami plot from the meta-analysis of ADHD and MDD GWAS. SNP rs12658032 on chromosome 5 was associated with both ADHD (p = 1.15 × 10^–7) as shown in red and with MDD (p = 1.18 × 10^–10) as shown in blue to a genome-wide significant level and was also genome-wide significant in meta-analysis (p = 1.54 × 10^–16). This SNP was located in a protein-coding gene desert. Non-protein-coding genes are shown in red. Genes are defined according to residence within the LD block of index SNP. The x-axis is chromosomal position in base pairs and the y-axis is the p value (− log10 p value) of the association of the SNP with both disorders.