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. 2021 Apr 1;11:7353. doi: 10.1038/s41598-021-86802-1

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Forest plot showing GWAS associations of rs8084351. To investigate pleiotropy, rs8084351 was tested for associations across 37 phenotypes covering various aspects of health and functioning. rs8084351 was associated mainly with mental health phenotypes. It also demonstrated associations with cognition and neuroticism. p = non-corrected p value. *Results unavailable for rs8084351 so a proxy SNP—rs7505145—was used.