Fig. 1. LOGODetect workflow.
a The inputs of LOGODetect include GWAS summary statistics for two traits and a reference panel for LD estimation. b Scan statistic is defined over a region, as the LD-weighted inner product of two z-score vectors in this region. A large absolute value of the scan statistic would hint at local genetic correlation. c LOGODetect identifies genome segments showing consistent associations with two different traits.