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. 2021 Apr 1;12:2033. doi: 10.1038/s41467-021-22334-6

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — The Y-axis shows the statistical power assessed by three different metrics: a, d signal points detection rate measures sensitivity at the SNP level, b, e signal segments detection rate measures sensitivity at the segment level, and c, f G-score jointly measures specificity and sensitivity. The heritability represents the trait heritability on chromosome 1 and the proportion of heritability represents the proportion of the trait heritability explained by the signal regions. Significance cutoffs for gwas-pw are adjusted so that the empirical type I error rate is controlled at 0.05. Details on the above three metrics and the adjustment procedure for the significance cutoff are discussed in the “Methods” section. Source data are provided as a Source Data file.