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. 2021 Apr 1;12(4):344. doi: 10.1038/s41419-021-03639-2

Fig. 5. EBV-LMP1 induces BNIP3 through the ERK/HIF1α pathway.

Fig. 5

A After treatment of different inhibitors for 24 h, the expression of BNIP3 and LC3І/ІІ in NPC cells by Western blots. B After treatment of 2ME2 for 24 h, the expression of HIF1α and BNIP3 in NPC cells by Western blots. C After treatment of 2ME2 for 24 h, the mRNA expression of BNIP3 in NPC cells by quantitative RT-PCR. Data are expressed as means ± S.D. of three experiments. *p < 0.05. D After treatment of 2ME2 or PD98059 for 24 h, the expression of p-ERK and HIF1α in CM, HM, and KM cells by Western blots. UN untreated.