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. 2021 Apr 1;12(4):338. doi: 10.1038/s41419-021-03619-6

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A Cell viability was measured by CCK-8 after RKO and HCT116 cells were treated with different concentrations of UTD1 for 72 h or 1 µg/ml UTD1 for different time-points. B Morphology of cells treated with UTD1 for 0, 12, and 24 h. Scale bar = 10 μm. C Colony formation showed UTD1 reduced colony formation of RKO and HCT116 cells. All experiments were performed in triplicate. Results were presented as mean ± SD, ***p < 0.001, ****p < 0.0005 vs. control group.