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. 2021 Apr 1;11:7400. doi: 10.1038/s41598-021-86921-9

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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The expression values of the five potential transporters are different in the responsive vs. resistant patients and can predict patient survival. (a) Boxplot showing the difference in the expression values of the five potential transporters in the responsive vs. resistant patients in an erlotinib clinical trial (GSE33072). The p-value was computed from Student’s t-test by comparing the gene expression in responders versus nonresponders. (b) Cox proportional hazard survival analysis showing how expression values of different genes affect patient survival in the TCGA lung cancer data set, with p-values illustrating the significance of the analysis.