Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Apr 1;11:7347. doi: 10.1038/s41598-021-86762-6

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Characterization of PTXNR-TTZ ADNs: (a) SEM image of PTXNR-TTZ ADNs. (b) The zeta potential (ξ) of PTXNR-TTZ was observed − 17.1 ± 3.83 mV in DI water. (c) Contour plot of response surface analysis showing % conjugation efficiency of TTZ on the surface of PTXNRs. In response surface analysis, two factors, PTXNR concentration and TTZ concentration were optimized for the highest conjugation efficiency. Each concentration factor had three levels. For PTXNR, the concentration levels were 5, 10, and 15 mg/ml, and for TTZ the levels were 0.5, 1.0, and 1.5 mg/ml, respectively. Each concentration was replicated at least three times resulting in a total of 27 experimental units. A maximum of ~ 95% conjugation efficiency was obtained using 5 mg/ml PTXNR and 0.5 mg/ml TTZ. The experiment was designed according to a complete randomized (CR) model using JMP statistical software.