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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: Addiction. 2020 Dec 18;116(5):1262–1269. doi: 10.1111/add.15280

Table 2.

Mean comparisons between classes identified up to 12-months following treatment on outcomes at 3 years post-treatment in COMBINE based on most-likely class membership

Non-responder Class 1: Low Functioning (≈10%) Non-responder Class 2: Average Functioning (≈20%) Non-responder Class 3: High Functioning (≈23%) Responders: Abstainers/ Low-risk Drinkers (48%)
Sample size range by group* 50 – 67 106 – 138 126 – 158 129 – 275
Percent Drinking Days (n = 638) M (95% Confidence Interval) 39.11a (30.29, 47.92) 39.53a (33.01, 46.04) 40.66a (34.54, 46.77) 19.68b (15.79, 23.58)
Drinks per Day (n = 411, abstainers excluded) M (95% Confidence Interval) 3.92a (2.83, 5.01) 3.55a (2.62, 4.48) 2.85a (2.30, 3.39) 0.89b (0.66, 1.11)
Drinks per Drinking Day (n = 638) M (95% Confidence Interval) 10.83a (9.03, 12.63) 10.13a (8.67, 11.59) 7.68b (6.73, 8.62) 5.43c (4.35, 6.52)
Percent Heavy Drinking Days (n = 638) M (95% Confidence Interval) 32.86a (24.40, 41.32) 29.31a (23.62, 35.00) 27.89a (22.52, 33.27) 7.49b (5.04, 9.93)
SF-12: Physical Health T-Score (n = 457) M (95% Confidence Interval) 45.51a (42.32, 48.71) 49.27ab (47.61, 50.93) 51.19b (49.55, 52.83) 51.61b (50.39, 52.84)
SF-12: Mental Health T-Score (n = 457) M (95% Confidence Interval) 38.06a (34.39, 41.73) 43.82b (42.09, 45.55) 51.25c (49.67, 52.84) 49.87c (48.42, 51.31)
WHOQOL-BREF: Physical Health (n = 591) M (95% Confidence Interval) 23.59a (22.23, 24.95) 27.25b (26.54, 27.96) 29.74c (29.16, 30.32) 29.36c (28.83, 29.89)
WHOQOL-BREF: Psychological Domain (n = 591) M (95% Confidence Interval) 18.52a (17.35, 19.70) 21.37b (20.78, 21.97) 24.22c (23.72, 24.72) 23.76c (23.30, 24.22)
WHOQOL-BREF: Social Relationships Domain (n = 590) M (95% Confidence Interval) 8.64a (7.88, 9.39) 10.03b (9.61, 10.45) 11.57c (11.21, 11.92) 11.54c (11.26, 11.83)
WHOQOL-BREF: Environment Domain (n = 591) M (95% Confidence Interval) 26.92a (25.15, 28.69) 29.72b (28.87, 30.57) 32.79c (32.09, 33.50) 32.71c (32.13, 33.28)

Note. SF-12=Short Form Health Survey, WHOQOL-BREF=World Health Organization Quality of Life Assessment-BREF. Means sharing a subscript in a row indicate means that are not significantly different from each other based on Tukey post-hoc comparisons.

*

Sample sizes ranged based on missingness on the various outcome variables.