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. 2021 Apr 1;11:7418. doi: 10.1038/s41598-021-86846-3

Table 2.

POAG incidence in ESRD patients, KTRs, and healthy controls.

Group N POAG Incidence Duration (person- years) Incidence rate (/1,000 person-years) Unadjusted Model 1 Model 2
HR (95% CI) P HR (95% CI) P HR (95% CI) P
Healthy Control 10,955 77 64,358.35 1.20 1 (Ref.) 1 (Ref.) 1 (Ref.)
ESRD 10,955 180 53,507.48 3.36 2.83 (2.17–3.70)  < 0.0001 2.95 (2.26–3.85)  < 0.0001 1.43 (0.97–2.12) 0.07
KTR 10,955 200 62,107.74 3.22 2.69 (2.07–3.50)  < 0.0001 2.72 (2.09–3.54)  < 0.0001 1.41 (0.96–2.07) 0.08
ESRD 10,955 180 53,507.48 3.36 1 (Ref.) 1 (Ref.) 1 (Reference)
KTR 10,955 200 62,107.74 3.22 0.95 (0.78–1.17) 0.65 0.928 (0.76–1.14) 0.47 1.02 (0.83–1.26) 0.84

Model 1: Cox proportional hazard (PH) regression model adjusted for age and sex.

Model 2: Cox proportional hazard (PH) regression model adjusted for age, sex, diabetes mellitus, hypertension, dyslipidemia, income, and Charlson comorbidity index.

POAG primary open-angle glaucoma, HR hazard ratio, CI confidence interval, ESRD end stage renal disease, KTR kidney transplantation recipients.