Table 1.

Sample origins of sequenced PDX tumors and non-PDX controls.

Sample type		PDX tumor	Primary tumor	Cell line
Breast cancer	PDX	✓
	Control			✓
Glioblastoma	PDX	✓
	Control		✓	✓
Lung cancer	PDX	✓
	Control		✓	✓
Ovarian cancer	PDX	✓
	Control			✓
Bladder cancer	PDX	✓
	Control		✓
Colorectal cancer	PDX	✓
	Control		✓	✓
Pancreatic cancer	PDX	✓
	Control		✓

Controls are samples not exposed to mouse environment and murine viruses, and are either corresponding primary tumor, primary cell culture, or both.