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. 2021 Mar 19;8:650368. doi: 10.3389/fcvm.2021.650368

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Copyright © 2021 Li, Zhao, Zhu, Wang, Li, Li, Li, Wu and Ma.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The protective effect of sweroside on ischemia–reperfusion (IR)-induced myocardial injury ex vivo. After pretreatment with various doses of sweroside, the rat heart was isolated and then subjected to IR. (A) Determination of myocardial infarct size using TTC staining. (B–E) Comparison of the difference in heart rate, left ventricular developed pressure (LVDP), positive first-order derivative of ventricular pressure (+dp/dt), and negative first-order derivative of ventricular pressure (–dp/dt) between groups. Data are presented as the mean ± standard deviation, n = 6. *P < 0.05; **P < 0.01; NS, not significant.