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. 2021 Mar 19;12:629379. doi: 10.3389/fphar.2021.629379

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Copyright © 2021 Duan, Zhang, Yang, Su, Zhou, Lo, Cai, Qiao, Li, Huang, Wang, Mo and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Baicalin showed anti-ferroptosis effect on hemin-treated PCN (A) Representative pictures of live/dead cell staining assay and DHE assay in hemin-induced PCN treated with baicalin. Bar = 200μm (B) The ratio of living cells was counted in different groups (n = 4) (C) Relative fluorescence intensity statistics of the ROS concentration in different groups (n = 4). The experiments were repeated at least three times with three replicates and data were expressed as mean ± SD. ^## p < 0.01 compared with the control group and *p < 0.05 and **p < 0.01 compared with the hemin-treated group.