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. 2021 Mar 19;12:625712. doi: 10.3389/fimmu.2021.625712

Table 1.

Percentage of PMN-MDSC during CHMI.

Time point Parasitemic Aparasitemic
% PMN-MDSC of PBMCs (CI: 95%) p-value
Baseline 1.67 (1.10; 2.54) 1.46 (0.79; 2.70) 0.2338
C+7 1.87 (1.25; 2.80) 1.56 (0.95; 2.58) 0.2338
C Malaria* C+14** 3.25 (2.14; 4.95)* 0.66 (0.42; 1.04)** 0.0002
C Treat2* 3.22 (1.99; 5.20)* 0.0002
C Treat3* 4.45 (2.91; 6.82)* <0.0001
C+21 2.21 (1.51; 3.22) 0.90 (0.55; 1.47) 0.0031

Values are given as the geometric mean of the % PMN-MDSC in PBMCs and their respective 95% confidence interval (CI). P-values are calculated as result of multiple comparison of participants PMN-MDSC % in PBMCs between aparasitemic and parasitemic participants corrected for the different days analyzed. Statistically significant p-values are given as bold values. PMN-MDSC percentage at time points labeled with (*) in parasitemic were compared to the respective control measurement performed at time point C+14 from aparasitemic volunteers (**).