Table 1.
Time point | Parasitemic | Aparasitemic | ||
---|---|---|---|---|
% PMN-MDSC of PBMCs (CI: 95%) | p-value | |||
Baseline | 1.67 (1.10; 2.54) | 1.46 (0.79; 2.70) | 0.2338 | |
C+7 | 1.87 (1.25; 2.80) | 1.56 (0.95; 2.58) | 0.2338 | |
C Malaria* | C+14** | 3.25 (2.14; 4.95)* | 0.66 (0.42; 1.04)** | 0.0002 |
C Treat2* | 3.22 (1.99; 5.20)* | 0.0002 | ||
C Treat3* | 4.45 (2.91; 6.82)* | <0.0001 | ||
C+21 | 2.21 (1.51; 3.22) | 0.90 (0.55; 1.47) | 0.0031 |
Values are given as the geometric mean of the % PMN-MDSC in PBMCs and their respective 95% confidence interval (CI). P-values are calculated as result of multiple comparison of participants PMN-MDSC % in PBMCs between aparasitemic and parasitemic participants corrected for the different days analyzed. Statistically significant p-values are given as bold values. PMN-MDSC percentage at time points labeled with (*) in parasitemic were compared to the respective control measurement performed at time point C+14 from aparasitemic volunteers (**).