TABLE 1.
Name | TS2 | TS14 | TS2TS14 | Name | TS2 | TS14 | TS2TS14 |
---|---|---|---|---|---|---|---|
Inter alpha-trypsin inhibitor | 1.2 ± 0.7 | 1.9 ± 0.7 | 1.6 ± 0.5 | Galectin-1 | 1.3 ± 0.3 | 1.9 ± 0.4 | 2.1 ± 0.4 |
AE-binding protein 1 | 0.7 ± 0.2 | 2.0 ± 0.5 | 1.2 ± 0.3 | Galectin-7 | 2.0 ± 0.6 | 2.8 ± 0.8 | 4.8 ± 1.4 |
Alpha-2-HS-glycoprotein | 0.7 ± 0.3 | 2.2 ± 1.3 | 0.9 ± 0.3 | Gc-globulin | 1.7 ± 0.8 | 4.1 ± 2.0 | 6.0 ± 3.7 |
Alpha-2-macroglobulin | 1.7 ± 1.0 | 2.0 ± 0.6 | 2.2 ± 0.6 | Gelsolin | 2.6 ± 0.7 | 2.4 ± 0.9 | 5.0 ± 1.7 |
Annexin-8 | 6.4 ± 2.2 | 5.5 ± 1.9 | 15.0 ± nd a | H2-Q9 | 1.9 ± 1.3 | 2.7 ± 1.1 | 2.9 ± 1.1 |
Apolipoprotein A-I | 2.7 ± 1.8 | 3.3 ± 1.9 | 4.5 ± 1.8 | Hemopexin | 1.0 ± 0.4 | 1.9 ± 0.5 | 1.5 ± 0.5 |
Apolipoprotein H | 1.6 ± 0.8 | 2.6 ± 1.2 | 2.3 ± 0.8 | Ig gamma-2B | 1.8 ± 0.5 | 2.3 ± 0.8 | 3.5 ± 1.2 |
Beta-globin | 2.2 ± 0.6 | 2.9 ± 1.1 | 6.7 ± 3.3 | Ig gamma-3 | 1.1 ± 0.4 | 1.9 ± 0.4 | 1.8 ± 0.4 |
Biglycan | 2.8 ± 2.4 | 3.0 ± 1.6 | 3.6 ± 1.8 | Ig kappa chain V-V | 1.2 ± 0.8 | 5.1 ± 2.7 | 2.9 ± 1.1 |
Carboxypeptidase A3 | 1.6 ± 0.4 | 2.1 ± 0.5 | 3.2 ± 1.1 | Kallikrein j | 2.0 ± 0.8 | 2.4 ± 0.6 | 5.1 ± 0.6 |
Cathepsin B heavy chain | 1.3 ± 0.6 | 1.9 ± 0.6 | 1.6 ± 0.3 | Kininogen-1 | 2.2 ± 0.5 | 2.9 ± 0.6 | 5.5 ± 0.2 |
Cathepsin H | 1.2 ± 0.6 | 2.4 ± 0.8 | 2.0 ± 0.6 | Lumican | 1.6 ± 0.7 | 2.6 ± 1.3 | 2.3 ± 0.4 |
Cathepsin S | 1.0 ± 0.5 | 2.2 ± 0.7 | 1.5 ± 0.4 | Mast cell protease 4 | 1.5 ± 0.2 | 1.7 ± 0.2 | 2.4 ± 0.5 |
Caveolin-1 | 2.0 ± 0.8 | 3.1 ± 1.4 | 3.1 ± 0.0 | MIF | 1.1 ± 0.6 | 2.7 ± 1.1 | 1.8 ± 0.5 |
Cavin-1 | 2.1 ± 0.4 | 3.5 ± 0.9 | 8.7 ± 0.4 | Myelin protein zero | 1.6 ± 0.7 | 2.1 ± 1.1 | 1.7 ± 0.4 |
Coagulation factor XIIIa | 2.5 ± 1.0 | 3.8 ± 1.5 | 7.8 ± nd a | Osteoglycin | 2.3 ± 0.7 | 2.3 ± 0.9 | 4.5 ± 1.6 |
Collagen alpha-1(I) chain | 4.2 ± 0.5 | 1.7 ± 0.2 | 6.8 ± 1.0 | p24 gamma-1 | 2.1 ± 1.1 | 3.3 ± 1.7 | 1.4 ± 1.0 |
Collagen alpha-1(III) chain | 3.7 ± 2.2 | 2.8 ± 1.3 | 5.8 ± 2.7 | p35/Annexin A1 | 2.7 ± 1.2 | 2.7 ± 0.9 | 7.4 ± 3.7 |
Collagen alpha-1(IV) chain | 1.6 ± 0.6 | 1.8 ± 0.6 | 2.2 ± 0.4 | p36/Annexin A2 | 2.7 ± 1.2 | 2.7 ± 0.9 | 7.4 ± 3.7 |
Collagen alpha-1(V) chain | 3.9 ± 1.7 | 4.1 ± 1.6 | 9.3 ± 0.8 | PCPE-1 | 2.2 ± 0.4 | 1.9 ± 0.4 | 3.6 ± 0.5 |
Collagen alpha-1(VI) chain | 2.2 ± 0.8 | 1.9 ± 0.6 | 3.4 ± 0.9 | PDI A6 | 1.8 ± 0.7 | 2.1 ± 0.7 | 2.9 ± 0.9 |
Collagen alpha-1 (XIV) chain | 3.6 ± 0.7 | 2.3 ± 0.5 | 8.2 ± 2.5 | Periostin | 1.0 ± 0.5 | 2.2 ± 0.8 | 1.3 ± 0.4 |
Collagen alpha-2(I) chain | 3.1 ± 0.7 | 1.6 ± 0.2 | 4.6 ± 0.6 | Proapolipoprotein A-II | 3.5 ± 2.5 | 4.9 ± 3.2 | 11.9 ± 7.9 |
Collagen alpha-2(V) chain | 1.8 ± 0.3 | 1.7 ± 0.3 | 2.8 ± 0.3 | Prolargin | 2.9 ± 0.9 | 2.6 ± 0.8 | 5.8 ± 1.3 |
Collagen alpha-2(VI) chain | 2.5 ± 0.7 | 2.2 ± 0.6 | 4.1 ± 0.0 | Protein unc-80 homolog | 1.8 ± 0.6 | 2.0 ± 0.2 | 3.5 ± 1.4 |
Collagen alpha-3(VI) chain | 4.7 ± 1.3 | 2.1 ± 0.6 | 8.0 ± 1.2 | Serpin A1c | 1.1 ± 0.3 | 2.4 ± 1.0 | 2.1 ± 0.5 |
Complement C3 | 1.8 ± 1.4 | 4.3 ± 3.4 | 2.3 ± 0.8 | Serpin A1d | 0.8 ± 0.5 | 2.8 ± 1.3 | 1.0 ± 0.4 |
Complement C4-B | 0.3 ± 0.1 | 2.7 ± 1.0 | 0.6 ± 0.2 | Serpin B6 | 4.7 ± 2.5 | 3.9 ± 2.4 | 8.0 ± 1.9 |
Complement factor B | 0.9 ± 0.2 | 2.0 ± 0.4 | 1.8 ± 0.5 | Protein serpinb6e | 1.3 ± 0.3 | 2.3 ± 0.6 | 2.5 ± 0.1 |
Complement factor H | 1.0 ± 0.3 | 1.8 ± 0.5 | 1.7 ± 0.6 | Serum albumin | 3.2 ± 1.7 | 4.2 ± 2.4 | 12.6 ± 9.7 |
Corneodesmosin | 1.5 ± 0.4 | 1.7 ± 0.4 | 2.2 ± 0.4 | Siderophilin | 2.2 ± 0.7 | 2.8 ± 1.1 | 5.2 ± 2.5 |
Cystatin-3 | 2.4 ± 0.6 | 2.7 ± 0.8 | 7.0 ± 3.7 | Stromelysin-1/MMP3 | 0.4 ± 0.1 | 1.5 ± 0.3 | 0.5 ± 0.1 |
Dermatopontin | 2.0 ± 0.4 | 1.6 ± 0.2 | 3.1 ± 0.6 | Susd 4 | 2.3 ± 0.7 | 2.4 ± 1.1 | 3.9 ± 1.1 |
Dermokine | 1.1 ± 0.3 | 1.4 ± 0.3 | 1.4 ± 0.2 | Transcobalamin II | 0.8 ± 0.5 | 2.2 ± 1.1 | 0.8 ± 0.2 |
nd: not determined.
The 68 extracellular and cell surface potential substrates are reported together with the average P/C ratio from at least two experiments for ADAMTS2, ADAMTS14 or ADAMTS2 and ADAMTS14. When several peptides were identified for a protein, the ratios from the peptide giving the highest value are reported for illustration. All the peptides and ratios are reported in supplemental.