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. 2021 Feb 9;12(7):1096–1105. doi: 10.1111/1759-7714.13878

FIGURE 5.

FIGURE 5

EGFR pathway‐independent resistance mechanisms in patients who developed acquired resistance to EGFR‐TKIs. (a) Incidence of small cell lung cancer transformation between gefitinib/erlotinib/afatinib and osimertinib. (b) KRAS mutation incidence between gefitinib/erlotinib/afatinib and osimertinib. (c) MET amplification incidence between gefitinib/erlotinib/afatinib and osimertinib. (d) PIK3A mutation incidence between gefitinib/erlotinib/afatinib and osimertinib