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. 2021 Mar 19;11:657615. doi: 10.3389/fonc.2021.657615

Table 1.

Characteristics of patients in baseline analysis.

Characteristics Training set P value Test set P value
Responders Non-responders Responders Non-responders
Age, median (range) 63 (35–84) 64 (36–78) 0.52 63 (29–75) 62 (41–77) 0.86
 Male 64 (36–84) 64 (36–78) 63 (29–75) 58 (41–74)
 Female 55 (43–79) 61 (37–72) 64 (43–72) 74 (62–77)
Sex, No. (%)
 Male 68 (83.95%) 44 (78.57%) 0.42 31 (91.18%) 22 (84.62%) 0.71
 Female 13 (16.05%) 12 (21.43%) 3 (8.82%) 4 (15.38%)
Smoking history, No. (%)
 Non-smokers 22 (27.16%) 17 (30.36%) 0.68 8 (23.53%) 8 (30.77%) 0.53
 Smokers 59 (72.84%) 39 (69.64%) 26 (76.47%) 18 (69.23%)
Pathological type, No. (%)
 Adenocarcinoma 37 (45.68%) 29 (51.79%) 0.75 18 (52.94%) 13 (50.0%) 0.87
 Others 44 (54.32%) 27 (48.21%) 16 (47.06%) 13 (50.0%)
Distant metastasis, No. (%)
 Absence 21 (25.93%) 5 (8.93%) 0.01* 8 (23.53%) 2 (7.69%) 0.20
 Presence 60 (74.07%) 51 (91.07%) 26 (76.47%) 24 (92.31%)
Treatment strategy, No. (%)
 Monotherapy 37 (45.68%) 31 (55.36%) 0.27 18 (52.94%) 19 (73.08%) 0.11
 Combination therapy 44 (54.32%) 25 (44.64%) 16 (47.06%) 7 (26.92%)
Rad-score (P25–P75)
 Target lesions −0.46 (−0.60, −0.30) −0.41(−0.55, −0.21) 0.27 −0.42 (−0.57, −0.21) −0.39 (−0.57, −0.22) 0.54
 Largest target lesion −0.20 (−0.21, −0.18) −0.19 (−0.20, −0.17) 0.10 −0.20 (−0.21, −0.16) −0.19 (−0.20, −0.17) 0.89

*P value < 0.05.