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. 2021 Mar 19;11:655826. doi: 10.3389/fonc.2021.655826

Table 3.

The multivariate logistic regression analysis of early death in patients with advanced epithelial ovarian cancer.

Characteristic FIGO Stage III FIGO Stage IV
OR 95% CI P-value OR 95% CI P-value
Age (years)
≤ 63 Ref Ref
64–76 2.90 2.17, 3.89 <0.001* 1.53 1.14, 2.04 0.004*
≥77 4.80 3.44, 6.72 <0.001* 2.80 1.96, 3.99 <0.001*
Race
White Ref Ref
Black 1.24 0.80, 1.86 0.317 1.12 0.74, 1.66 0.586
Others 0.73 0.42, 1.20 0.234 1.51 0.98, 2.28 0.054
Marital status
Single Ref Ref
Married 0.72 0.52, 1.01 0.051 0.89 0.64, 1.24 0.472
Divorced or Separated 1.18 0.78, 1.78 0.426 0.91 0.58, 1.41 0.664
Widowed 1.10 0.75, 1.62 0.630 0.91 0.60, 1.38 0.657
Histological subtype
Endometrioid carcinoma Ref Ref
Serous cystadenocarcinoma 1.08 0.69, 1.77 0.740 0.37 0.23, 0.58 <0.001*
Mucinous cystadenocarcinoma 4.16 2.25, 7.81 <0.001* 1.14 0.63, 2.07 0.677
Clear cell adenocarcinoma 3.28 1.79, 6.09 <0.001* 0.74 0.38, 1.40 0.351
Laterality
Only one side Ref Ref
Both sides 1.12 0.88, 1.43 0.357 0.94 0.73, 1.22 0.647
Unkown 0.92 0.44, 1.86 0.826 0.51 0.28, 0.90 0.022
Tumor size (mm)
≤ 27 Ref Ref
≥28 1.26 0.86, 1.92 0.255 1.44 0.93, 2.33 0.116
Liver metastases
No Ref
Yes 1.86 1.26, 2.71 <0.001*
Unknown 1.49 0.50, 4.22 0.468
Lung metastases
No Ref
Yes 2.19 1.44, 3.29 <0.001*
Unknown 1.02 0.36, 3.03 0.967
CA125
Negative Ref Ref
Positive 2.70 1.21, 7.29 0.028*
Unkown 2.45 1.07, 6.75 0.054
Surgery
No surgery Ref Ref
Local resection 0.18 0.08, 0.39 <0.001* 0.37 0.19, 0.71 0.003*
Debulking or pelvic exenteration 0.12 0.08, 0.18 <0.001* 0.15 0.11, 0.22 <0.001*
Surgery but the specific operation unknown 0.16 0.01, 1.05 0.107 0.39 0.04, 2.25 0.340
Chemotherapy
No Ref Ref
Yes 0.08 0.06, 0.10 <0.001* 0.09 0.07, 0.11 <0.001*

FIGO, Federation International of Gynecology and Obstetrics; OR, Odds Ratio; CI, Confidence Interval; Ref, Reference;

*

p < 0.05.