Table 3.
The multivariate logistic regression analysis of early death in patients with advanced epithelial ovarian cancer.
| Characteristic | FIGO Stage III | FIGO Stage IV | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P-value | OR | 95% CI | P-value | |
| Age (years) | ||||||
| ≤ 63 | Ref | Ref | ||||
| 64–76 | 2.90 | 2.17, 3.89 | <0.001* | 1.53 | 1.14, 2.04 | 0.004* |
| ≥77 | 4.80 | 3.44, 6.72 | <0.001* | 2.80 | 1.96, 3.99 | <0.001* |
| Race | ||||||
| White | Ref | Ref | ||||
| Black | 1.24 | 0.80, 1.86 | 0.317 | 1.12 | 0.74, 1.66 | 0.586 |
| Others | 0.73 | 0.42, 1.20 | 0.234 | 1.51 | 0.98, 2.28 | 0.054 |
| Marital status | ||||||
| Single | Ref | Ref | ||||
| Married | 0.72 | 0.52, 1.01 | 0.051 | 0.89 | 0.64, 1.24 | 0.472 |
| Divorced or Separated | 1.18 | 0.78, 1.78 | 0.426 | 0.91 | 0.58, 1.41 | 0.664 |
| Widowed | 1.10 | 0.75, 1.62 | 0.630 | 0.91 | 0.60, 1.38 | 0.657 |
| Histological subtype | ||||||
| Endometrioid carcinoma | Ref | Ref | ||||
| Serous cystadenocarcinoma | 1.08 | 0.69, 1.77 | 0.740 | 0.37 | 0.23, 0.58 | <0.001* |
| Mucinous cystadenocarcinoma | 4.16 | 2.25, 7.81 | <0.001* | 1.14 | 0.63, 2.07 | 0.677 |
| Clear cell adenocarcinoma | 3.28 | 1.79, 6.09 | <0.001* | 0.74 | 0.38, 1.40 | 0.351 |
| Laterality | ||||||
| Only one side | Ref | Ref | ||||
| Both sides | 1.12 | 0.88, 1.43 | 0.357 | 0.94 | 0.73, 1.22 | 0.647 |
| Unkown | 0.92 | 0.44, 1.86 | 0.826 | 0.51 | 0.28, 0.90 | 0.022 |
| Tumor size (mm) | ||||||
| ≤ 27 | Ref | Ref | ||||
| ≥28 | 1.26 | 0.86, 1.92 | 0.255 | 1.44 | 0.93, 2.33 | 0.116 |
| Liver metastases | ||||||
| No | – | – | – | Ref | ||
| Yes | – | – | – | 1.86 | 1.26, 2.71 | <0.001* |
| Unknown | – | – | – | 1.49 | 0.50, 4.22 | 0.468 |
| Lung metastases | ||||||
| No | – | – | – | Ref | ||
| Yes | – | – | – | 2.19 | 1.44, 3.29 | <0.001* |
| Unknown | – | – | – | 1.02 | 0.36, 3.03 | 0.967 |
| CA125 | ||||||
| Negative | Ref | Ref | ||||
| Positive | 2.70 | 1.21, 7.29 | 0.028* | – | – | – |
| Unkown | 2.45 | 1.07, 6.75 | 0.054 | – | – | – |
| Surgery | ||||||
| No surgery | Ref | Ref | ||||
| Local resection | 0.18 | 0.08, 0.39 | <0.001* | 0.37 | 0.19, 0.71 | 0.003* |
| Debulking or pelvic exenteration | 0.12 | 0.08, 0.18 | <0.001* | 0.15 | 0.11, 0.22 | <0.001* |
| Surgery but the specific operation unknown | 0.16 | 0.01, 1.05 | 0.107 | 0.39 | 0.04, 2.25 | 0.340 |
| Chemotherapy | ||||||
| No | Ref | Ref | ||||
| Yes | 0.08 | 0.06, 0.10 | <0.001* | 0.09 | 0.07, 0.11 | <0.001* |
FIGO, Federation International of Gynecology and Obstetrics; OR, Odds Ratio; CI, Confidence Interval; Ref, Reference;
p < 0.05.