. 2021 Mar 19;11:636751. doi: 10.3389/fonc.2021.636751

Table 1.

Clinicopathological features and CD169⁺/CD68⁺ ratio in lymph node sinus macrophages (LySMs) from 294 patients with gastric cancer.

Clinicopathological feature	n	CD169⁺cells/CD68⁺cells in LySMs
Clinicopathological feature	n	<0.65	≥0.65	P
Age
< 70 (y)	147	62	85	0.198
≥ 70 (y)	147	73	74	0.198
Sex
Female	109	49	60	0.799
Male	185	86	99	0.799
Histology
Intestinal type	142	64	78	0.778
Diffuse type	152	71	81	0.778
Depth of invasion
m, sm	135	66	69	0.346
mp, ss, se, si	159	69	90	0.346
LN metastasis
Negative	175	80	95	0.932
Positive	119	55	64	0.932
Distant metastasis
Negative	270	123	147	0.675
Positive	24	12	12	0.675
Lymphatic invasion
Negative	92	45	47	0.487
Positive	202	90	112	0.487
Vascular invasion
Negative	141	63	78	0.683
Positive	153	72	81	0.683
Tumor-stroma ratio
Low	202	96	106	0.413
High	92	39	53	0.413
CD8⁺cells/mm² in tumor
< 287	147	90	57	<0.001
≥ 287	147	45	102	<0.001

LySMs, lymph node sinus macrophages; m, mucosa; sm, submucosa; mp, muscularis propria; ss, subserosa; se, serosa exposure; si, serosa invasion; LN, lymph node.