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. 2021 Apr 2;147(7):1973–1991. doi: 10.1007/s00432-021-03601-x

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© The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021

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Fig. 2 — Venn diagram of genes significantly upregulated upon IFNG treatment and NLRC5 overexpression in DFT1 and DFT2 cells. Genes were defined as significantly upregulated when false discovery rate (FDR) < 0.05 and log₂FC ≥ 2.0. Total number of genes upregulated for each treatment is indicated in parentheses under the sample name. The box shows genes upregulated in all four treatments: (i) IFNG-treated DFT1 cells (DFT1.WT + IFNG), (ii) IFNG-treated DFT2 cells (DFT2.WT^RV + IFNG), (iii) NLRC5-overexpressing DFT1 cells (DFT1.NLRC5), and (iv) NLRC5-overexpressing DFT2 cells (DFT2.NLRC5). See Online Resource 1 for a full list of differentially expressed genes and Online Resource 10 for description of devil-specific genes (LOC symbols)