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. 2021 Mar 26;9(9):2110–2122. doi: 10.12998/wjcc.v9.i9.2110

Table 4.

Pharmacokinetic characteristics of topical nonsteroidal anti-inflammatory drugs patches[23-29]


Loxoprofen sodium
Ketoprofen
Diclofenac sodium
Flurbiprofen
Indometacin
Ibuprofen
Log P value 1.97 2.94 4.31 3.81 4.42 3.51
Cmax in ng/mL 61.20 891.36 0.81 43.00 27.00 556.00
Tmax in h 82.30 7.60 16.90 20.00 16.00 14.40
T1/2 in h 7.8 NA NA 13.90 11.55 NA