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. 2021 Feb 24;32(4):866–885. doi: 10.1681/ASN.2020060832

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Copyright © 2021 by the American Society of Nephrology

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Figure 4. — MRI analysis of outflow vein. (A and B) Representative images from the MRI of the outflow vein after vehicle or 1,25 NP delivery at day 28. (C) The average lumen vessel area measured by MRI is significantly increased in 1,25 NP group compared with the vehicle group at day 28. (D) The average PSV measured by MRI is significantly decreased in 1,25 NP group compared with vehicle group at day 14 after AVF creation. (E) The average blood flow measured by MRI is significantly increased in 1,25 NP group compared with vehicle group at both days 14 and days 28 after AVF placement. (F) The average wall shear stress (WSS) is significantly decreased in 1,25 NP group compared with vehicle group at day 14 after AVF creation. (G) The pulsatility index (PI) is not significantly changed in 1,25 NP group compared with vehicle group at any time points after AVF placement. (H) The resistivity index (RI) is significantly decreased in 1,25 NP group compared with vehicle group at day 28 after AVF placement. (I) The Reynolds number (Re) is not significantly changed in 1,25 NP group compared with vehicle group at any time points after AVF placement. Each bar represents mean±SEM of n≥3. Two-way ANOVA was performed. *P<0.05, **P<0.01, ***P<0.001. CCA, common carotid artery.