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. 2021 Mar 19;12:646179. doi: 10.3389/fgene.2021.646179

TABLE 1.

HiChIP target genes at EOC risk loci.

Locus CV Counts HiChIP Target Genes
1p34.3 5 RP11-109P14.10, MTF1, INPP5B, GNL2*, LINC01137, ZC3H12A
2q31.1 17 LINC01116*, LINC01117, HOXD1, AC079305.8, MIR4444-2, HNRNPA3
3q25.31 54 PLCH1, AC104472.1, C3orf33, SSR3, TIPARP, TIPARP-AS1*, LEKR1, LINC00880, RP11-6F2.5, LINC00881, CCNL1, RNA5SP146, RP11-550I24.2, LINC00886*, PA2G4P4
5p15.33 1 TRIP13*
8q24.21 32 CASC8, CASC11, RP11-419K12.1, RP11-89M16.1, MYC, PVT1
9p22.2 11 BNC2*
9q34.2 35 ABO, RP11-430N14.4, RALGDS, SURF4*, C9orf96, REXO4, ADAMTS13
10p12.31 5 RP11-275N1.1, NEBL-AS1, NEBL*, MLLT10*
15q26.1 28 RN7SL346P, SEMA4B*, RP11-154B12.3, IQGAP1*, HDDC3*, RP11-387D10.2, RP11-387D10.3, UNC45A*, AC068831.3, RCCD1*, AC068831.6, VPS33B, AC068831.10, PRC1*, PRC1-AS1, AC068831.11, AC068831.12, RP11-661P17.1, CTD-2313J17.1, FAM174B*
17q12 10 GGNBP2,DHRS11*, SYNRG*, DDX52, RP11-697E22.1, RP11-697E22.2, RP11-697E22.3, HNF1B, YWHAEP7, AC124789.1, ARHGAP23*
17q21.31 244 AC002117.1, HEXIM2*, CTD-2020K17.1, FMNL1*, DND1P1, RP11-259G18.1, KANSL1*, NSF, WNT3, ARL17B
17q21.32 96 SKAP1*, RP11-456D7.1, RNU6-1152P, HOXB3*, HOXB-AS3, HOXB-AS2, HOXB4*, MIR10A, HOXB7*, HOXB8*, HOXB9, HOXB6, HOXB5, HOXB2, HOXB-AS1, Y_RNA, COPZ2*, CBX1, SNX11*, MIR1203, RP11-357H14.17, RP11-433M22.2, HOXB-AS4, MIR196A1
19p13.11 15 CTC-429P9.4, SMIM7*, TMEM38A, HAUS8*, MYO9B, USE1, OCEL1, NR2F6*, AC010646.3, USHBP1, ANO8*, GTPBP3*, CTD-3131K8.2, PGLS*, ABHD8, DDA1*, PLVAP, CTD-2521M24.9, BST2, MVB12A*, CTD-2521M24.6, CTD-2521M24.8, CTD-2521M24.5
22q12.1 96 PITPNB, TTC28-AS1, MIR3199-2, TTC28, CHEK2, CCDC117, CTA-292E10.6, XBP1, HSCB, RN7SL162P, ZNRF3-AS1, ZNRF3, RHBDD3, EWSR1*, MIAT*, CTA-373H7.7, CTA-211A9.5, CTA-292E10.7

Underlined loci or genes are shown in HiChIP results of both EOC cell lines.

*Genes are differentially expressed between normal samples and tumor samples of EOC in at least one of GSE18520, GSE27651, and GSE54388 dataset (Fold change ≥ 2 and adjust p-value < 0.01).