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. 2021 Apr 1;203(7):802–808. doi: 10.1164/rccm.202010-3779PP

Figure 1.

Figure 1.

Integrative model for the origin of childhood atopy and asthma focuses on exposures that shape prenatal microbial and immune development and influence epigenetic imprinting that affect microbial and immune vertical transmission, postnatal microbial and immune development, and clinical outcomes in later childhood.