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Proposed AD-age score visualization and its distribution in the discovery and replication samples. a Illustration of the proposed AD-age scores with a linear and a piecewise definition of the weight (age) function (see the “Methods” section). b, c Cases (AD) and controls (CN) age distribution in the discovery, composed of next generation sequencing data, and in the replication, composed of SNP-array imputed data, and d, e their respective AD-age score distributions
