Table 3.

Sample sizes, minor allele frequency, and imputation quality for the identified variants. MAF minor allele frequency, R-square (Rsq) Imputation quality

Gene(s)	RS id	Consequence	SNP (hg19)	Discovery		Replication
				N	MAF	N	MAF	Rsq
KIF21B	rs2297911	synonymous	1:200959302:G:A	11,006	0.17391	21,631	0.1769	1
USH2A	rs111033333	missense	1:216270469:G:A	11,126	0.00085	19,544	0.00132	0.81
RAB10	rs149622307	synonymous	2:26332640:T:C	11,057	0.00045	9833	0.00076	0.85
TREM2	rs75932628	missense	6:41129252:C:T	11,076	0.00591	21,176	0.00606	0.93
PILRA	rs2405442	synonymous	7:99971313:T:C	11,022	0.29836	21,631	0.30567	0.94
MS4A6A	rs12453	synonymous	11:59945745:T:C	11,114	0.3941	21,481	0.39015	0.99
RIN3	rs150221413	missense	14:93022240:G:T	11,020	0.00082	17,652	0.00131	0.8
TAOK2	rs4077410	synonymous	16:29998200:A:G	11,063	0.47966	21,631	0.48195	0.94
NSF/MAPT/ KANSL1	rs199533	synonymous	17:44828931:G:A	11,094	0.20367	21,631	0.19931	0.99
ABCA7	rs547447016	frameshift	19:1047507:AGGAGCAG:A	11,006	0.00313	18,356	0.00311	0.88