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. 2021 Apr 1;14:53. doi: 10.1186/s13045-021-01065-7

Table 4.

Univariate analysis of 2-year clinical outcomes

RI NRM LFS OS GRFS aGVHD grade II–IV aGVHD grade III–IV cGVHD ext. cGVHD
MSD 31.6% [29.2–34%] 13% [11.4–14.7%] 55.4% [52.8–57.9%] 67.4% [64.8–69.8%] 39% [36.4–41.5%] 28.9% [26.8–31.1%] 10.5% [9.1–12%] 38.8% [36.3–41.3%] 19.5% [17.5–21.7%]
Haplo 26% [21.5–30.8%] 22.9% [18.8–27.3%] 51% [45.7–56.2%] 58.8% [53.3–63.9%] 40.6% [35.4–45.7%] 36.3% [31.5–41.1%] 15.2% [11.9–19%] 32% [27.1–37.1%] 11.9% [8.6–15.8%]
p 0.017 0.001 0.07 0.001 0.74 0.002 0.005 0.009 0.001

RI, relapse incidence; NRM, non-relapse mortality; LFS, leukemia-free survival; OS, overall survival; GVHD, graft versus host disease; GRFS, GVHD-free/relapse-free survival; KPS, Karnofsky performance status; ATG, anti-thymocyte globulin; PTCy, post-transplant cyclophosphamide; RIC, reduced intensity conditioning; MAC, myeloablative conditioning; PB, peripheral blood; BM, bone marrow